Scleroderma

Six patterns are described for scleroderma, and they differ mainly in what is blocking the channels and in how much of the picture is depletion. Three are obstruction patterns: Wind-Cold-Damp, which gives cool pale tight skin and joints that ache in damp weather; Damp-Heat, which gives hot red or purplish skin and swelling early in the illness; and Phlegm in the channels, where congealed fluids form hard lumps and a leathery surface. Two describe the consequences of long obstruction: Blood Stagnation, with board-like skin and fixed stabbing pain, and Qi and Blood deficiency, with thin atrophic papery skin and wasting. The sixth, Kidney and Spleen Yang deficiency, is the deepest stage, recognised by skin that is hard yet paper thin and by limbs that never warm. Patterns commonly overlap and succeed one another, so the formula is revised as the disease moves.

Avoid in pregnancy   Caution in pregnancy

Avoid in pregnancy   Caution in pregnancy

Avoid in pregnancy   Caution in pregnancy

Avoid in pregnancy   Caution in pregnancy

Avoid in pregnancy   Caution in pregnancy

Avoid in pregnancy   Caution in pregnancy

• Favour warm cooked easily digestible food such as soups and congees, and avoid cold raw food.
• The general principle is warm, cooked and easy to digest: soups, stews, congees and steamed vegetables, which support the Spleen and Stomach as the source of Qi and Blood. Ice-cold drinks, raw salads, excess dairy, greasy and sugary food are limited because they add Cold, Dampness and Phlegm. Bone broth, black sesame and dark leafy greens, with small amounts of red meat, support Blood, and where Damp-Heat is present cooling foods such as cucumber and mung beans may be advised instead.

Avoid in pregnancy   Caution in pregnancy

How the tradition treats scleroderma, with the herbs, formulas and points used for it.

Principles

• Warm and unblock the skin channels where cold-damp is obstructing.
• Nourish Qi and Blood where the skin is thin and atrophic.
• Move Blood and resolve stasis where the skin is hard and leathery.
• Coordinate with medical care, because internal organ involvement is the main determinant of outcome.
• The common aim is to unblock the channels and bring Qi and Blood freely back to the skin, and the means divide by pattern: disperse Wind, warm Cold, dry Dampness or clear Heat where pathogens dominate, and supplement Qi, Blood, Yang or Yin where depletion dominates, transforming Phlegm and invigorating Blood where the two have combined. Treatment is rarely static. As obstruction clears, the underlying deficiency often becomes obvious, and a formula that dispelled Cold-Dampness is replaced by one that tonifies Spleen and Kidney. Points are chosen to support that strategy and to treat the affected areas directly.

Herbs used

Formulas

• Ma Huang Fu Zi Xi Xin Tang
• Xuan Bi Tang
• Huang Qi Gui Zhi Wu Wu Tang
• Shen Tong Zhu Yu Tang
• Xiao Huo Luo Dan
• You Gui Yin

Acupoints

• LI-4 (Hegu)Avoid in pregnancy
• GB-20 (Fengchi)
• GB-34 (Yanglingquan)
• SP-6 (Sanyinjiao)Avoid in pregnancy
• LI-11 (Quchi)
• SP-9 (Yinlingquan)
• ST-36 (Zusanli)
• qihai-ren-6Avoid in pregnancy
• SP-10 (Xuehai)
• BL-17 (Geshu)
• ST-40 (Fenglong)
• BL-23 (Shenshu)
• BL-20 (Pishu)
• guanyuan-ren-4Avoid in pregnancy

What to expect

• The tradition describes skin softening and symptom relief over months, not weeks.
• Internal organ involvement progresses independently, which is why medical monitoring is essential.
• Skin changes may stabilise rather than reverse.
• Improvement is usually noticed in the order of warmth in the hands and feet, then less joint stiffness, then better energy, often within the first month. Softening of the skin comes more slowly, typically becoming apparent after two to four months, and progress is measured in small practical gains such as buttoning a shirt or less tightness across the chest. Plans usually run six to twelve months, with the formula adjusted every few weeks as the pattern shifts, and chronic cases may continue at lower intensity.

• Regular medical monitoring of lungs, heart, kidneys and blood pressure is essential.
• Protect the hands from cold and injury; Raynaud's commonly coexists.
• Do not stop prescribed treatment without medical advice.

• TCM is described as complementary to conventional care: . Organ monitoring and prescribed treatment continue; herbs are used for the skin and constitutional pattern alongside them.
• TCM is described as usable alongside conventional scleroderma care provided everyone involved knows the plan. Blood-moving herbs, Dang Gui and Chuan Xiong among them, may interact with anticoagulants or antiplatelet drugs, and Huang Qi may influence immune function, so the rheumatologist should be told what is being taken. A full medication and supplement list is brought to each consultation, prescribed drugs are not stopped without the prescriber's agreement, and new symptoms are reported to the medical team promptly.

Pregnancy gathers Qi and Blood towards the fetus, so depletion may deepen, in particular deficiency of both Qi and Blood and deficiency of Kidney Yang. Blood-moving formulas, Shen Tong Zhu Yu Tang among them, are considered unsuitable because they can stimulate the uterus, and strong dispersing herbs such as Ma Huang and Fu Zi are avoided. Gentle tonics, Huang Qi Gui Zhi Wu Wu Tang above all, are preferred, and acupuncture is often the first choice, with LI-4, SP-6 and lower abdominal points avoided and moxibustion on the back and abdomen generally avoided. The obstetrician should be part of the plan.

Milk production continues to drain Qi and Blood, so deficiency patterns may persist. Bitter cold herbs such as Huang Bo can reach breast milk and may cause diarrhoea in the infant, and strong warming dispersing herbs such as Ma Huang and Fu Zi are avoided. Milder warming tonics, Huang Qi Gui Zhi Wu Wu Tang among them, are generally considered safe, acupuncture has no direct contraindication, and the infant's sleep and digestion are watched when the mother takes herbs.

Localised scleroderma is more common in children than the systemic form, and children's patterns tend toward excess, with Wind-Cold-Damp obstruction the usual culprit: tight cool skin, a pale tongue and a tight pulse. Treatment expels the pathogen with milder versions of formulas such as Ma Huang Fu Zi Xi Xin Tang, at doses scaled to age and weight; acupuncture is frequently swapped for acupressure or tuina, and courses are shorter because children respond quickly, with care not to over-disperse. Fever or difficulty swallowing needs immediate medical attention.

In older adults a deficiency component is almost always present, most often Kidney and Spleen Yang deficiency, or deficiency of both Qi and Blood, with thin papery skin rather than thick swelling, deep fatigue, cold intolerance and weak digestion. Treatment prioritises gentle tonification, with You Gui Yin, and with Huang Qi Gui Zhi Wu Wu Tang where warmth is the greater need, at roughly two thirds of the adult dose; multiple medications mean clotting-affecting herbs, Dan Shen and Chuan Xiong among them, are used cautiously. Acupuncture is generally well tolerated, expectations are set for slowing progression rather than reversal, and timelines are longer.

Urgent-sign guidance is based on standard sources: NHS anaphylaxis, NHS cellulitis, NHS Stevens-Johnson syndrome, NHS melanoma.

• Xi Xin
• Wei Ling Xian
• Fang Ji
• Dan Shen
• Tao Ren
• Hong Hua
• Chuan Xiong
• San Qi
• Ban Xia
• Tian Nan Xing
• Dan Nan Xing
• LI-4 (Hegu)
• SP-6 (Sanyinjiao)

Wind-Cold-Damp gives skin tightening with a cold sensation, joint and muscle pain worse in cold weather, and stiffness. Damp-Heat gives redness, warmth and a purple-red hue with pain eased by cold.

The deeper patterns describe the later picture. Qi and Blood deficiency gives thin atrophic papery skin with muscle wasting and fatigue. Blood stagnation gives skin hard as leather that cannot be pinched, with dark discolouration and fixed stabbing pain. Phlegm in the channels gives fixed pain with hard non-pitting swelling or subcutaneous lumps, and Kidney and Spleen Yang deficiency gives thin papery skin with cold limbs and early-morning diarrhoea.

The classical literature places scleroderma within skin impediment, a Bi syndrome in which pathogens obstruct the channels and collaterals of the skin. The obstruction is either external, from Wind, Cold, Dampness or Heat, or internal, from deficiency of Qi, Blood and Yang. What follows depends on which dominates: cold and tight skin, hot inflamed skin, or thin atrophic skin.

As the condition continues, stagnant Qi and Blood congeal into Phlegm and stasis, and the skin becomes leathery and cannot be pinched. That progression explains why one disease presents so differently at different stages, and why treatment both dispels pathogens in the early excess stages and tonifies in the later deficiency ones.

How it connects

In TCM scleroderma rarely travels alone. Joint pain frequently accompanies skin hardening because both arise from the same pathogenic obstructions, Wind, Cold and Dampness lodged in the channels: when these block the flow of Qi and Blood in the joints, pain and stiffness result, and when they settle in the skin it tightens and hardens, so treating the underlying obstruction often eases both. Acid reflux is another common companion, reflecting the Spleen and Stomach's struggle with Dampness and Cold, since the same Yang deficiency that fails to warm the skin also weakens digestive fire. Aversion to cold with cold limbs is almost a hallmark, especially in Yang-deficiency or Cold-Damp patterns, and improves as the core pattern is warmed. Because scleroderma is progressive, an early Cold-Damp obstruction can gradually drain Qi and Blood into deficiency and then congeal into Blood stasis and Phlegm, with Yang deficiency as the deepest stage, so several patterns often show at once and different areas of the body may carry different features. The skin's temperature and texture are the strongest clues: cold and puffy, hot and red, thin and wasted, or thick and leathery each point elsewhere. Rapid skin tightening, difficulty swallowing, breathlessness or severe joint pain need prompt medical assessment.

What a practitioner looks for

• Skin texture: papery and thin suggests deficiency; hard and leathery suggests stagnation.
• Temperature and colour: cold tightening suggests cold-damp; purple-red warmth suggests damp heat.
• Swelling: hard non-pitting swelling or lumps suggests Phlegm in the channels.
• Organ red flags: breathlessness, new severe hypertension, or difficulty swallowing need urgent medical care.

The practitioner first asks about temperature and colour, since the earliest stage usually reads as either cold or hot. Cool pale skin that tightens gradually and worsens in cold weather, with a pale tongue, thin white coat and tight pulse, points to Wind-Cold-Damp. Hot red or purplish skin that may swell, with dark scanty urine, a red tongue carrying a greasy yellow coat and a rapid slippery pulse, points to Damp-Heat.

As the illness lingers, the practitioner looks for depletion. Thin atrophic sallow skin, muscle wasting, deep fatigue and thinning hair, with a pale tongue bearing teeth marks and a deep thready pulse, indicate Qi and Blood deficiency. A leathery board-like surface that cannot be pinched, dark or purplish in colour, with stiff painful joints, a dark tongue with purple spots under a thick greasy coat and a slippery or thready pulse, indicate that Blood stasis and Phlegm have combined.

The last pattern is recognised by paradox: skin that is hard yet paper thin, with limbs that stay cold, deep tiredness, sore lower back and knees and loose stools. A pale swollen tongue with a white coat and a deep thready weak pulse confirm Kidney and Spleen Yang deficiency. Throughout, the practitioner asks about breathing, swallowing and blood pressure, because organ involvement rather than the skin decides the outcome.

Real PubMed records for the TCM clinical evidence discussed above, selected by condition name and title relevance. They are references, not proof of benefit.

• Gastrointestinal involvement in systemic sclerosis: diagnosis and management.. Current opinion in rheumatology, 2018. PMID: 30234725.
• Complementary therapies for patients with systemic sclerosis.. Journal of scleroderma and related disorders, 2019. PMID: 35382503.

Selected real PubMed records for this condition or its wider research context. They are laboratory, mechanistic or other research references, not proof of benefit.

• EULAR recommendations for the treatment of systemic sclerosis: 2023 update.. Annals of the rheumatic diseases, 2025. PMID: 39874231.
• Botulinum Toxin for Refractory Digital Ischemia and Ulcers in Systemic Sclerosis: A Systematic Review and Meta-Analysis.. JAMA dermatology, 2026. PMID: 41369954.
• Incidence and prevalence of systemic sclerosis globally: a comprehensive systematic review and meta-analysis.. Rheumatology (Oxford, England), 2021. PMID: 33630060.